陈金阳

|  个人简介

陈金阳，博士，副教授，硕士生导师。2017年获武汉大学博士学位，2017年6月入职伟德国际1946源于英国BETVLCTOR伟德唯一官网。主要从事分析化学专业教学与纳米传感方向研究工作。先后主持国家自然科学基金、湖北省自然科学基金等科研项目7项，发表SCI论文30余篇，获授权国家发明专利1项。曾获“刘道玉创造研究奖”、“唐敖庆化学奖”、“伟德国际1946源于英国优秀班主任”等奖励和荣誉称号。

|  教学及人才培养

1. 主讲《分析化学》《分析化学实验》等本科生课程和《材料技术与表征》《现代分析测试技术》等研究生课程

2. 承担本科生学位论文及综合化学实验指导工作

3. 担任分析化学学科研究生导师

 |  主要科研课题

1. 主持：国家自然科学基金青年基金项目（22004031），2021-2023年

2. 主持：湖北省自然科学基金面上项目（2023AFB996），2023-2025年

3. 主持：湖北省自然科学基金青年项目（2019CFB182），2019-2021年

4. 主持：湖北省教育厅科学研究计划项目（Q20182504），2018-2019年

|  代表性论文论著 

1. Qingli Chai, Jinyang Chen*, Shasha Zeng, Ting Zhu, Jintao Chen, Chunjiao Qi, Guobin Mao, Yucheng Liu, Closed cyclic DNA machine for sensitive logic operation and APE1 detection. Small, 2023, 19, 2207736.

2. Shasha Zeng, Jinyang Chen*, Qingli Chai, Ting Zhu, Guobin Mao, Label-free and low-background FEN1 sensing based on cleavage-induced ligation of bifunctional dumbbell DNA and in-situ signal readout, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 290, 122295.

3. Yanyun Zou, Jinyang Chen*, Qingli Chai, Ting Zhu, Shasha Zeng, Yucheng Liu, Stimuli responsive colorimetric sensor based on bifunctional pyrophosphate-triggered controlled release and enhancing activity of CoOOH nanozyme. Sensors and Actuators B-Chemical, 2022, 369, 132215-132215.

4. Ting Zhu, Jinyang Chen*, Qingli Chai, Shasha Zeng, Yucheng Liu, Stable and sensitive sensor for alkaline phosphatase based on target-triggered wavelength tuning of fluorescent copper nanoclusters. Analytica Chimica Acta, 2022, 1232, 340453.

5. Yanyun Zou, Qingli Chai, Ting Zhu, Xiaoxiao Yu, Guobin Mao, Ningxing Li, Jinyang Chen*, Guosong Lai, Simultaneously colorimetric detection and effective removal of mercury ion based on facile preparation of novel and green enzyme mimic. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 266, 120410.

6. Qingli Chai, Yuqi Wan, Yanyun Zou, Ting Zhu, Ningxing Li, Jinyang Chen*, Guosong Lai, Ultrasensitive and turn-on homogeneous Hg²⁺ sensing based on a target-triggered isothermal cycling reaction and dsDNA-templated copper nanoparticles. Analytical Methods, 2021, 13, 3521-3526.

7. Yuqi Wan, Qingli Chai, Yanyun Zou, Guobin Mao, Jinyang Chen*, A versatile fluorescent nanobeacon lighted by DNA-templated copper nanoparticles and the application in isothermal amplification detection. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 262, 120102.

8. Haoyu Chen, Li Wu, Yuqi Wan, Lulu Huang, Ningxing Li, Jinyang Chen*, Guosong Lai, One-step rapid synthesis of fluorescent silicon nanodots for a hydrogen peroxide-related sensitive and versatile assay based on the inner filter effect. Analyst, 2019, 144, 4006-4012.

9. Songbai Tian, Zhen Zhang, Jinyang Chen, Mingyuan Du, Zheng Li, Hai Yang, Xinghu Ji, Zhike He*, Digital analysis with droplet-based microfluidic for the ultrasensitive detection of β-gal and AFP. Talanta, 2018, 186, 24-28

10. Jinyang Chen, Xinghu Ji, Zhike He*, Smart composite reagent composed of double-stranded DNA-templated copper nanoparticle and SYBR Green I for hydrogen peroxide related biosensing. Analytical Chemistry, 2017, 89, 3988-3995.

11. Jinyang Chen, Yongen Xu, Xinghu Ji, Zhike He*, Enzymatic polymerization-based formation of fluorescent copper nanoparticles for the nuclease assay. Sensors and Actuators B: Chemical, 2017, 239, 262-269.

12. Yucheng Liu, Jinyang Chen, Mingyuan Du, Xinxin Wang, Xinghu Ji, Zhike He*, The preparation of dual-functional hybrid nanoflower and its application in the ultrasensitive detection of disease-related biomarker. Biosensors and Bioelectronics, 2017, 92, 68-73.

13. Ningxing Li, Jinyang Chen, Ming Luo, Chaohui Chen, Xinghu Ji, Zhike He*, Highly sensitive chemiluminescence biosensor for protein detection based on the functionalized magnetic microparticles and the hybridization chain reaction. Biosensors and Bioelectronics, 2017, 87, 325-331.

14. Jiao Zheng, Tai Ye, Jinyang Chen, Li Xu, Xinghu Ji, Chuluo Yang, Zhike He*, Highly sensitive fluorescence detection of heparin based on aggregation induced emission of a tetraphenylethene derivative. Biosensors and Bioelectronics, 2017, 90, 245-250.

15. Chen Su, Chen Liu, Jinyang Chen, Zilin Chen, Zhike He*, Simultaneous determination of zeatin and systemin by coupling graphene oxide-protected aptamers with catalytic recycling of DNase I. Sensors and Actuators B: Chemical, 2016, 230, 442.

16. Jingwen Lan, Jinyang Chen, Ningxing Li, Xinghu Ji*, Minxia Yu, Zhike He*, Microfluidic generation of magnetic-fluorescent Janus microparticles for biomolecular detection. Talanta, 2016, 151, 126-131.

17. Chen Liu, Jinyang Chen, Guobin Mao, Chen Su, Xinghu Ji, Zhike He*, Target-induced structure switching of a hairpin aptamer for the fluorescence detection of zeatin. Analytical Methods, 2016, 8 (30), 5957-5961.

18. Jinyang Chen, XinghuJi, Philip Tinnefeld, Zhike He*, Multifunctional dumbbell-shaped DNA-templated selective formation of fluorescent silver nanoclusters or copper nanoparticles for sensitive detection of biomolecules. ACS Applied Materials & Interfaces, 2016, 8, 1786-1794.

19. Jinyang Chen, Yucheng Liu, XinghuJi, Zhike He*, Target-protecting dumbbell molecular probe against exonucleases digestion for sensitive detection of ATP and streptavidin. Biosensors and Bioelectronics, 2016, 83, 221-228.

20. Jinyang Chen, Yufei Liu, Tai Ye, Xia Xiang, Xinghu Ji, Zhike He*, A novel droplet dosing strategy-based versatile microscale biosensor for detection of DNA, protein and ion. Sensors and Actuators B: Chemical, 2015, 215, 206-214.

21. Jinyang Chen, Xinghu Ji, Zhike He*, High-throughput droplet analysis and multiplex DNA detection in the microfluidic platform equipped with a robust sample-introduction technique. Analytica Chimica Acta, 2015, 888, 110-117.

22. Jinyang Chen, Guohua Zhou, Yufei Liu, Tai Ye, Xia Xiang, Xinghu Ji*, Zhike He*, Assembly-line manipulation of droplets in microfluidic platform for fluorescence encoding and simultaneous multiplexed DNA detection. Talanta, 2015, 134, 271-277.

23. Tai Ye, Jinyang Chen, Yufei Liu, Xinghu Ji*, Guohua Zhou, Zhike He*, Periodic fluorescent silver clusters assembled by rolling circle amplification and their sensor application. ACS Applied Materials & Interfaces, 2014, 6 (18), 16091-16096.

24. Xiang, Xia, Liyang Shi, Ming Luo, Jinyang Chen, Xinghu Ji*, Zhike He*, Stepwise reagent introduction-based droplet platform for multiplexed DNA sensing. Biosensors and Bioelectronics, 2013, 49, 403-409.

|  发明专利

1. 陈金阳；柴青丽；万雨琦，一种基于双链DNA模板荧光纳米铜的荧光分子信标及其制备方法和应用，专利号：ZL202110337265.0，授权公告日：2023-3-15.

|  主要荣誉及获奖        

1. 伟德国际1946源于英国教学优秀奖，2020年、2022年

2. 伟德国际1946源于英国优秀班主任，2020年

3. 刘道玉创造研究奖，2016年

4. 唐敖庆化学奖，2015年

(Updated: 10 Oct, 2023)